The Sickle Cell Mutation: A Molecular Trade-Off | HS-LS1-3
$3.25
📌 Prepare your students for the NYS Regents Science Exams with this fully 3D-aligned cluster assessment built from the NYSSLS Performance Expectations. This rigorous set mimics the format, language, and structure of actual Regents clusters.
🧬 In this Sickle Cell Variation cluster, students analyze genetic mutations, explore evolutionary trade-offs, and evaluate medical treatments under real-world constraints using authentic data from NCBI, Nature, and Blood Journal.
🔍 What’s Included:
3 full-color stimuli (text, diagrams, tables)
6 three-dimensional assessment questions:
✅ 3 Multiple Choice
✅ 3 Constructed Response (short CER, argumentation, explanation)
Performance Expectation alignment: HS-LS1-3, HS-LS3-1, HS-LS4-1, HS-ETS1-3
Explicit SEP + CCC integration: Patterns, Cause & Effect, Analyzing & Interpreting Data, Engaging in Argument from Evidence
Differentiated complexity (PLD 3–4)
Detailed Answer Key with 3D alignment and distractor analysis
🎯 Skills Assessed:
✔ Central Dogma & Protein Structure
✔ Genetic Inheritance and Population Trends
✔ Natural Selection & Adaptation
✔ Bioethical Evaluation of Gene Editing & Treatment
✔ Data Interpretation & Scientific Reasoning
$3.25
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