The quote suggests that taking risks requires a certain strength of character or resilience ("mettle or constitution"). If someone lacks this inner fortitude, engaging in risky behavior is even more dangerous for them. When the negative outcomes of those risks materialize, they won't have the support of influential figures (like a "Twitter influencer") to bail them out or mitigate the consequences. Essentially, it warns that risk-taking without the ability to handle potential fallout is a recipe for trouble, and external help, like social media clout, won't be there to save you.
The quote is from Kapil Gupta
Credit: hand drawn+ AI Art (LumaAI with GPT 4.0) + Illustrator