Obesity & Brain: The Gut-Brain Axis

Obesity & Brain: The Gut-Brain Axis

Diet and Obesity Effects on Brain Structure and Function. The Influence of the Gut-Brain Axis

Obesity & Brain: The Gut-Brain Axis

The prevalence of Dementia and Obesity is increasing in almost all societies around the World. Unfortunately, the burden on individual and societal health has been underestimated.

- Recent expert estimates indicate an increase from 57 Million to 153 Million cases between 2019 and 2050. This threatens individual health and will significantly increase societal health costs.

- Previous research has detected the relationship between Obesity and Dementia, which translates into alterations in the structure and functions of the Brain.

- These alterations are due to Modifiable Risk Factors such as Obesity and Diet, which lead to Dysfunction in the Gut-Brain Axis (a well-identified neurochemical pathway by which the brain and gut communicate), ultimately causing damage to Brain Health and Cognitive Function.

- In this study, Neuroimaging (MRI) data from Epidemiological Studies and randomized clinical trials were used to analyze the underlying mechanisms and consequences of Obesity and Diet on Brain structure and function, as well as the role of the Gut-Brain Axis in Cognitive Aging and Brain Dysfunction.

- Research Highlights the beneficial impact of factors such as the Gut Microbiome, Obesity Control, and Dietary Polyphenols on Brain Health and Cognition.

- Likewise, the study emphasizes the need to understand the factors that drive Obesity and Accelerated Brain Aging to develop effective prevention strategies.

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